Recent Publications


  1. Shun Hirasawa, Takashi Kurashima, Takahiro Hasegawa, Kazunori Souma, Nobuhiro Kanomata, “Total Synthesis of (±)-Azaspirene via Crystallization-induced Diastereomer Transformation,,” Chem. Lett. 2022, 51, 985-988. [https://doi.org/10.1246/cl.220299]

  2. Shun Hirasawa, Tsuyoshi Masuda, Ken Mukai, Yusuke Miyoshi, Nobuhiro Kanomata, “Asymmetric synthesis of (–)-dehydro-exo-brevicomin with photoisomerisation–intramolecular acetalisation sequence,” Org. Biomol. Chem. 2021, 19, 6897-6903. [https://doi.org/10.1039/D1OB00952D]

  3. Narihito Ogawa, Sei Furukawa, Yuya Kosugi, Takayuki Takazawa, Nobuhiro Kanomata, “Biomimetic systems involving sequential redox reactions in glycolysis - the sulfur effect,” Chem. Commun. 2020, 56, 12917-12920. [https://doi.org/10.1039/D0CC05185C]

  4. Shun Hirasawa, Ken Mukai, Shinnosuke Sakai, Shinnosuke Wakamori, Takahiro Hasegawa, Kazunori Souma, Nobuhiro Kanomata, Narihito Ogawa, Mamoru Aizawa, and Makoto Emoto, “Elucidation of racemization process of azaspirene skeleton in neutral aqueous media,” J. Org. Chem. 2018, 83, 14457-14464. [https://doi.org/10.1021/acs.joc.8b02223]

  5. Makoto Emoto, Kyoko Yano, Batsuren Choijamts, Shinnosuke Sakai, Shun Hirasawa, Shinnosuke Wakamori, Mamoru Aizawa, Kazuki Nabeshima, Katsuro Tachibana, Nobuhiro Kanomata, “Azaspirene analogs inhibit the growth of human uterine carcinosarcoma in vitro and in vivo,” Anticancer Res. 2015, 35, 2739-2746. [https://ar.iiarjournals.org/content/35/5/2739.short]

  6. Nanako Mugishima, Nobuhiro Kanomata, Norihiko Akutsu, Hironobu Kubota, "Remote steric effects of C2-symmetric planar-chiral terpyridine ligands on copper-catalyzed asymmetric cyclopropanation reactions," Tetrahedron Letters, 2015, 56, 1898-1903. [https://doi.org/10.1016/j.tetlet.2015.02.103]

  7. Tomohiko Matsuo, Tatsuya Hattori, Akari Asaba, Naokazu Inoue, Nobuhiro Kanomata, Takefumi Kikusui, Reiko Kobayakawa, Ko Kobayakawa, "Genetic dissection of pheromone processing reveals main olfactory system-mediated social behaviors in mice," Proc. Natl. Acad. Sci. USA, 2015, 112, E311-E320. [https://doi.org/10.1073/pnas.1416723112]

  8. Ryo Maeda, Takehiko Wada, Tadashi Mori, Shigeyuki Kono, Nobuhiro Kanomata, Yoshihisa Inoue, "Planar-to-Planar Chirality Transfer in the Excited State. Enantiodif-ferentiating Photoisomerization of Cyclooctenes Sensitized by Planar-Chiral Paracyclophane," J. Am. Chem. Soc. 2011, 133, 10379-10381. [https://doi.org/10.1021/ja203781f]

  9. Yuko Izuchi, Hiroyuki Koshino, Yayoi Hongo, Nobuhiro Kanomata, and Shunya Takahashi, "Synthesis and Structural Revision of Phomopsin B, a Novel Polyketide Carrying a 10-Membered Cyclic-Ether Ring," Org. Lett. 2011, 13, 3360-3363. [https://doi.org/10.1021/ol2011117]

  10. Yuko Izuchi, Nobuhiro Kanomata, Hiroyuki Koshino, Yayoi Hongo, Tadashi Nakata, Shunya Takahashi, "Formal total synthesis of aspergillide A," Tetrahedron Asymmetry, 2011, 22, 246-251. [https://doi.org/10.1016/j.tetasy.2011.01.016]

  11. Nobuhiro Kanomata, Ryo Sakaguchi, Kazuki Sekine, Satomi Yamashita, and Hiroko Tanaka, "Enantioselective Cyclopropanation Reactions with Planar-Chiral Pyridinium Ylides. A Substituent Effect and A Remote Steric Effect," Adv. Synth. Catal. 2010, 352, 2966-2978. [https://doi.org/10.1002/adsc.201000079]

  12. Makoto Emoto, Yasuko Naganuma, Batsuren Choijamts, Toshiki Ohno, Hajime Yoshihisa, Nobuhiro Kanomata, Tatsuhiko Kawarabayashi and Mamoru Aizawa, "Novel chemoembolization using calcium-phosphate ceramic microsphere incorporating TNP-470, an anti-angiogenic agent," Cancer Sci. 2010, 101, 984-990. [https://doi.org/10.1111/j.1349-7006.2009.01479.x]

  13. Nobuhiro Kanomata, Jun Suzuki, Hironobu Kubota, Kiichiro Nishimura, and Terumichi Enomoto, "Synthesis of planar-chiral bridged bipyridines and terpyridines by metal-mediated coupling reactions of pyridinophanes," Tetrahedron Lett. 2009, 50, 2740-2743. [https://doi.org/10.1016/j.tetlet.2009.03.095]

  14. Nobuhiro Kanomata, Gou Mishima, and Jun Onozato, "Synchronized stereocontrol of planar chirality by crystallization-induced asymmetric transformation," Tetrahedron Lett. 2009, 50, 409-412. [https://doi.org/10.1016/j.tetlet.2008.11.021]

  15. M. Aizawa, T. Ohno, N. Kanomata, K. Yano, M. Emoto, "Anti-Tumorigenesis of Hollow Calcium-Phosphate Microsphere Loaded with Anti-Angiogenic Agent," Key Engineering Materials 2008, 361-363, 1215-1218. [https://doi.org/10.4028/www.scientific.net/KEM.361-363.1215]

  16. Nobuhiro Kanomata, Shinsuke Yamada, Takayuki Ohhama, Akira Fusano, Yoshiharu Ochiai, Jun Oikawa, Masahiro Yamaguchi, and Fumio Sudo, "Synthesis of Bridged Nicotinates Having [n](2,5)Pyridinophane Skeletons (n = 8-14)," Tetrahedron 2006, 62, 4128-4138. [https://doi.org/10.1016/j.tet.2006.02.002]

  17. Tsuyoshi Ueda, Nobuhiro Kanomata, and Hajime Machida, "Synthesis of Planar-Chiral Paracyclophanes via Samarium(II)-Catalyzed Intramolecular Pinacol Coupling," Org. Lett. 2005, 7, 2365-2368. [https://doi.org/10.1021/ol0506258]

  18. Nobuhiro Kanomata, "Development of stereocontrol of planar-chirality for N-containing cyclophanes," Fain Kemikaru 2003, 44, 5-13. (Japanese)

  19. Nobuhiro Kanomata and Jun Oikawa, "Adsorption-Induced Asymmetric Transformation of Planar-Chiral Pyridinophanes," Tetrahedron Lett., 2003, 44, 3625-3628. [https://doi.org/10.1016/S0040-4039(03)00699-3]

  20. Nobuhiro Kanomata, Satoshi Maruyama, Katsuhito Tomono, and Shinnosuke Anada, "A Simple Method Removing 2-Oxazolidinone and 2-Hydroxyethylamine Auxiliaries in Methoxide-Carbonate Systems for Synthesis of Planar-Chiral Nicotinate," Tetrahedron Lett., 2003, 44, 3599-3603. [https://doi.org/10.1016/S0040-4039(03)00698-1]

  21. Nobuhiro Kanomata, "Studies on Syntheses and Functional Properties of Structurally Unique Nitrogen Aromatics," Yuki Gosei Kagaku Kyoukaishi (J. Synth. Org. Chem., Jpn.)  2003, 61, 352-359 (Japanese). [https://doi.org/10.5059/yukigoseikyokaishi.61.352]

  22. Nobuhiro Kanomata and Yoshiharu Ochiai, "Stereocontrol of Molecular Jump-rope: Crystallization-induced Asymmetric Transformation of Planar-chiral Cyclophanes," Tetrahedron Lett., 2001, 42 , 1045-1048. [https://doi.org/10.1016/S0040-4039(00)02043-8]

  23. Nobuhiro Kanomata and Tadashi Nakata, "A Compact Chemical Miniature of a Holoenzyme, Coenzyme NADH Linked Dehydrogenase. Design and Synthesis of Bridged NADH Models and Their Highly Enantioselective Reduction," J. Am. Chem. Soc., 2000, 122, 4563-4568. [https://doi.org/10.1021/ja992990y]

  24. Nobuhiro Kanomata, "Biomimetic Oxidation and Asymmetric Reduction with Coenzyme NAD Analogs," Yuki Gosei Kagaku Kyoukaishi (J. Synth. Org. Chem., Jpn.)  1999, 57, 512-522 (Japanese). [https://doi.org/10.5059/yukigoseikyokaishi.57.512]

  25. Nobuhiro Kanomata and Tadashi Nakata, "Novel Pyridine-formation Reactions of 2-(Phosphoranylideneamino)acrylaldehydes with Acetylenic Esters. Synthesis of 2-Mono and 2,5-Disubstituted Nicotinates," Heterocycles , 1998, 48, 2551—2558. [https://doi.org/10.3987/COM-98-8314]

  26. Nobuhiro Kanomata, Masayuki Suzuki, Mamiko Yoshida, and Tadashi Nakata, "Biomimetic Oxidation of Aldehyde with NAD+ Models: Glycolysis-Type Hydrogen Transfer in an NAD+/NADH Model System," Angew. Chem., 1998, 110, 1506-1508; Angew. Chem. Int. Ed., 1998, 37, 1410-1412. [https://doi.org/10.1002/(SICI)1521-3773(19980605)37:10<1410::AID-ANIE1410>3.0.CO;2-G]

  27. Nobuhiro Kanomata, "Coenzyme Mimics for Asymmetric Induction. Design and Syntheses of Bridged NADH Models and Their Hightly Enantioselective Reduction," Kagaku To Kogyo (Chemistry and Chemical Industry) 1998, 51, 183-186. (Japanese)

  28. Nobuhiro Kanomata and Tadashi Nakata, "Highly Enantioselective Reduction with Novel, Bridged NADH Models," Angew. Chem., 1997, 109, 1263-1266; Angew. Chem. Int. Ed. Engl., 1997, 36, 1207-1211. [https://doi.org/10.1002/anie.199712071]

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