研究発表


論文等

  1. Shun Hirasawa, Takashi Kurashima, Takahiro Hasegawa, Kazunori Souma, Nobuhiro Kanomata, “Total Synthesis of (±)-Azaspirene via Crystallization-induced Diastereomer Transformation,,” Chem. Lett. 2022, 51, 985-988. [https://doi.org/10.1246/cl.220299]

  2. Shun Hirasawa, Tsuyoshi Masuda, Ken Mukai, Yusuke Miyoshi, Nobuhiro Kanomata, “Asymmetric synthesis of (–)-dehydro-exo-brevicomin with photoisomerisation–intramolecular acetalisation sequence,” Org. Biomol. Chem. 2021, 19, 6897-6903. [https://doi.org/10.1039/D1OB00952D]

  3. Narihito Ogawa, Sei Furukawa, Yuya Kosugi, Takayuki Takazawa, Nobuhiro Kanomata, “Biomimetic systems involving sequential redox reactions in glycolysis - the sulfur effect,” Chem. Commun. 2020, 56, 12917-12920. [https://doi.org/10.1039/D0CC05185C]

  4. Shun Hirasawa, Ken Mukai, Shinnosuke Sakai, Shinnosuke Wakamori, Takahiro Hasegawa, Kazunori Souma, Nobuhiro Kanomata, Narihito Ogawa, Mamoru Aizawa, and Makoto Emoto, “Elucidation of racemization process of azaspirene skeleton in neutral aqueous media,” J. Org. Chem. 2018, 83, 14457-14464. [https://doi.org/10.1021/acs.joc.8b02223]

  5. Makoto Emoto, Kyoko Yano, Batsuren Choijamts, Shinnosuke Sakai, Shun Hirasawa, Shinnosuke Wakamori, Mamoru Aizawa, Kazuki Nabeshima, Katsuro Tachibana, Nobuhiro Kanomata, “Azaspirene analogs inhibit the growth of human uterine carcinosarcoma in vitro and in vivo,” Anticancer Res. 2015, 35, 2739-2746. [https://ar.iiarjournals.org/content/35/5/2739.short]

  6. Nanako Mugishima, Nobuhiro Kanomata, Norihiko Akutsu, Hironobu Kubota, "Remote steric effects of C2-symmetric planar-chiral terpyridine ligands on copper-catalyzed asymmetric cyclopropanation reactions," Tetrahedron Letters, 2015, 56, 1898-1903. [https://doi.org/10.1016/j.tetlet.2015.02.103]

  7. Tomohiko Matsuo, Tatsuya Hattori, Akari Asaba, Naokazu Inoue, Nobuhiro Kanomata, Takefumi Kikusui, Reiko Kobayakawa, Ko Kobayakawa, "Genetic dissection of pheromone processing reveals main olfactory system-mediated social behaviors in mice," Proc. Natl. Acad. Sci. USA, 2015, 112, E311-E320. [https://doi.org/10.1073/pnas.1416723112]

  8. Ryo Maeda, Takehiko Wada, Tadashi Mori, Shigeyuki Kono, Nobuhiro Kanomata, Yoshihisa Inoue, "Planar-to-Planar Chirality Transfer in the Excited State. Enantiodif-ferentiating Photoisomerization of Cyclooctenes Sensitized by Planar-Chiral Paracyclophane," J. Am. Chem. Soc. 2011, 133, 10379-10381. [https://doi.org/10.1021/ja203781f]

  9. Yuko Izuchi, Hiroyuki Koshino, Yayoi Hongo, Nobuhiro Kanomata, and Shunya Takahashi, "Synthesis and Structural Revision of Phomopsin B, a Novel Polyketide Carrying a 10-Membered Cyclic-Ether Ring," Org. Lett. 2011, 13, 3360-3363. [https://doi.org/10.1021/ol2011117]

  10. Yuko Izuchi, Nobuhiro Kanomata, Hiroyuki Koshino, Yayoi Hongo, Tadashi Nakata, Shunya Takahashi, "Formal total synthesis of aspergillide A," Tetrahedron Asymmetry, 2011, 22, 246-251. [https://doi.org/10.1016/j.tetasy.2011.01.016]

  11. Nobuhiro Kanomata, Ryo Sakaguchi, Kazuki Sekine, Satomi Yamashita, and Hiroko Tanaka, "Enantioselective Cyclopropanation Reactions with Planar-Chiral Pyridinium Ylides. A Substituent Effect and A Remote Steric Effect," Adv. Synth. Catal. 2010, 352, 2966-2978. [https://doi.org/10.1002/adsc.201000079]

  12. Makoto Emoto, Yasuko Naganuma, Batsuren Choijamts, Toshiki Ohno, Hajime Yoshihisa, Nobuhiro Kanomata, Tatsuhiko Kawarabayashi and Mamoru Aizawa, "Novel chemoembolization using calcium-phosphate ceramic microsphere incorporating TNP-470, an anti-angiogenic agent," Cancer Sci. 2010, 101, 984-990. [https://doi.org/10.1111/j.1349-7006.2009.01479.x]

  13. Nobuhiro Kanomata, Jun Suzuki, Hironobu Kubota, Kiichiro Nishimura, and Terumichi Enomoto, "Synthesis of planar-chiral bridged bipyridines and terpyridines by metal-mediated coupling reactions of pyridinophanes," Tetrahedron Lett. 2009, 50, 2740-2743. [https://doi.org/10.1016/j.tetlet.2009.03.095]

  14. Nobuhiro Kanomata, Gou Mishima, and Jun Onozato, "Synchronized stereocontrol of planar chirality by crystallization-induced asymmetric transformation," Tetrahedron Lett. 2009, 50, 409-412. [https://doi.org/10.1016/j.tetlet.2008.11.021]

  15. M. Aizawa, T. Ohno, N. Kanomata, K. Yano, M. Emoto, "Anti-Tumorigenesis of Hollow Calcium-Phosphate Microsphere Loaded with Anti-Angiogenic Agent," Key Engineering Materials 2008, 361-363, 1215-1218. [https://doi.org/10.4028/www.scientific.net/KEM.361-363.1215]

  16. Nobuhiro Kanomata, Shinsuke Yamada, Takayuki Ohhama, Akira Fusano, Yoshiharu Ochiai, Jun Oikawa, Masahiro Yamaguchi, and Fumio Sudo, "Synthesis of Bridged Nicotinates Having [n](2,5)Pyridinophane Skeletons (n = 8-14)," Tetrahedron 2006, 62, 4128-4138. [https://doi.org/10.1016/j.tet.2006.02.002]

  17. Tsuyoshi Ueda, Nobuhiro Kanomata, and Hajime Machida, "Synthesis of Planar-Chiral Paracyclophanes via Samarium(II)-Catalyzed Intramolecular Pinacol Coupling," Org. Lett. 2005, 7, 2365-2368. [https://doi.org/10.1021/ol0506258]

  18. 鹿又宣弘，「Ｎ含有シクロファンの面不斉を立体制御する手法の開発」，ファインケミカル，2003, 32(19), 5-13.

  19. Nobuhiro Kanomata and Jun Oikawa, "Adsorption-Induced Asymmetric Transformation of Planar-Chiral Pyridinophanes," Tetrahedron Lett., 2003, 44, 3625-3628. [https://doi.org/10.1016/S0040-4039(03)00699-3]

  20. Nobuhiro Kanomata, Satoshi Maruyama, Katsuhito Tomono, and Shinnosuke Anada, "A Simple Method Removing 2-Oxazolidinone and 2-Hydroxyethylamine Auxiliaries in Methoxide-Carbonate Systems for Synthesis of Planar-Chiral Nicotinate," Tetrahedron Lett., 2003, 44, 3599-3603. [https://doi.org/10.1016/S0040-4039(03)00698-1]

  21. 鹿又宣弘，「特異な構造を有する含窒素芳香族化合物の合成と機能に関する研究」，有機合成化学協会誌，2003, 61, 352-359. [https://doi.org/10.5059/yukigoseikyokaishi.61.352]

  22. Nobuhiro Kanomata and Yoshiharu Ochiai, "Stereocontrol of Molecular Jump-rope: Crystallization-induced Asymmetric Transformation of Planar-chiral Cyclophanes," Tetrahedron Lett., 2001, 42 , 1045-1048. [https://doi.org/10.1016/S0040-4039(00)02043-8]

  23. Nobuhiro Kanomata and Tadashi Nakata, "A Compact Chemical Miniature of a Holoenzyme, Coenzyme NADH Linked Dehydrogenase. Design and Synthesis of Bridged NADH Models and Their Highly Enantioselective Reduction," J. Am. Chem. Soc., 2000, 122, 4563-4568. [https://doi.org/10.1021/ja992990y]

  24. 鹿又宣弘，「補酵素NADモデル分子を用いた生体酸化・不斉還元モデル反応」，有機合成化学協会誌，1999, 57, 512-522. [https://doi.org/10.5059/yukigoseikyokaishi.57.512]

  25. Nobuhiro Kanomata and Tadashi Nakata, "Novel Pyridine-formation Reactions of 2-(Phosphoranylideneamino)acrylaldehydes with Acetylenic Esters. Synthesis of 2-Mono and 2,5-Disubstituted Nicotinates," Heterocycles , 1998, 48, 2551—2558. [https://doi.org/10.3987/COM-98-8314]

  26. Nobuhiro Kanomata, Masayuki Suzuki, Mamiko Yoshida, and Tadashi Nakata, "Biomimetic Oxidation of Aldehyde with NAD+ Models: Glycolysis-Type Hydrogen Transfer in an NAD+/NADH Model System," Angew. Chem., 1998, 110, 1506-1508; Angew. Chem. Int. Ed., 1998, 37, 1410-1412. [https://doi.org/10.1002/(SICI)1521-3773(19980605)37:10<1410::AID-ANIE1410>3.0.CO;2-G]

  27. 鹿又宣弘，「補酵素の不斉還元機能を模倣する．−架橋型NADHモデルの設計・合成と不斉還元反応」，化学と工業 (化学のフロンティア'98特集号) ，1998, 51, 183-186.

  28. Nobuhiro Kanomata and Tadashi Nakata, "Highly Enantioselective Reduction with Novel, Bridged NADH Models," Angew. Chem., 1997, 109, 1263-1266; Angew. Chem. Int. Ed. Engl., 1997, 36, 1207-1211. [https://doi.org/10.1002/anie.199712071]

国際学会（抜粋）

  1. Narihito Ogawa, Sei Furukawa, Yuya Kosugi, Takayuki Takazawa, Nobuhiro Kanomata, “Biomimetic Oxidation in Glycolysis and Sulfur effect,” The International Chemical Congress of Pacific Basin Societies, Honolulu in U.S.A. (online), 2021年12月．

  2. Yuji Sato, Yusuke Miyashita, Nobuhiro Kanomata, “Determination of absolute configuration of D2 symmetric [10][10]parapyrazinophane,” The International Chemical Congress of Pacific Basin Societies, Honolulu in U.S.A. (online), 2021年12月．

  3. Ryohei Numaguchi, Takeshi Okumura, Shohei Nishibe, Katsuhiro Yoshizawa, Yasushi Furushima, Tamaka Nohara, Miyako Kato, Aya Saito, Tsuyoshi Masuda, Ryusuke Hako, Yuji Sato, Nobuhiro Kanomata, and Kazuo Tanaka, “Towards the Carbon Circulation Society: Direct Air Capture by Kawasaki CO2 Capture Technology and CO2 utilization,” Proceedings of the 15th Greenhouse Gas Control Technologies Conference 15-18 March 2021, Available at SSRN: http://dx.doi.org/10.2139/ssrn.3815348.

  4. Yusuke Miyashita, Masaki Kakinuma, Yuki Ono, and Nobuhiro Kanomata, “Parapyrazinophane - An Intrinsically Chiral Diazine-cyclophane and the Kinetics of Its Racemization,” 27th International Congress of Heterocyclic Chemistry, 京都, 2019年9月．

  5. Yusuke Miyashita and Nobuhiro Kanomata, “Asymmetric Catalysis of Racemization-Free Planar-Chiral Pyridinophanes Including Hemiacetal and Acetal Skeletons,” 27th International Congress of Heterocyclic Chemistry, 京都, 2019年9月．

  6. Tsuyoshi Masuda, Ken Mukai, Yusuke Miyoshi, and Nobuhiro Kanomata, “Highly Efficient Asymmetric Total Synthesis of (–)-Dehydro-exo-Brevicomin via Photoisomerization-Acetaliza-tion Strategy,” 27th International Congress of Heterocyclic Chemistry, 京都, 2019年9月．

  7. Ryutaro Ono, Yuichiro Tago, Yusuke Miyashita, Nobuhiro Kanomata, “Stereocontrol of planar-chiral bridged isonicotinamide via crystallization-induced asymmetric transformation,” 31st International Symposium on Chiral Discrimination (ISCD31, Chilarity2019), Bordeaux in France, 2019年7月．

特許（抜粋）

  1. 佐藤 裕，鹿又 宣弘，由渕 武，「置換ピペラジン化合物及び酸性ガス用の吸収剤、吸収液」，出願日：2016年9月8日，特願2016-175509．2017年3月2日，特願2017-38971（国内優先権出願）．2017年9月7日，特願2017-171802（国内優先権出願）．

  2. 2. 佐藤 裕，山中 康朗，古川 行夫，中井 浩巳，鹿又 宣弘，山本 浩之，「二酸化炭素吸収液及びその調製方法」，出願日：2012年2月6日，特開 2013-158718．